Custom hardware
Built around
the biology.
Our miniature lagoon reactors provide independent evolution channels, with carefully controlled culture conditions and continuous flow.
Directed evolution, developed in Zürich
Evolution.
Engineered
to accelerate.
Better proteins. Less waiting.
We’re building an automated platform that puts continuous evolution to work.
Supported by
Biology × Hardware × SoftwareOne integrated evolution platform
In final validationBuilding toward our first evolution run
The scienceContinuous protein evolution
Nature found a way.
We’re giving it pace.
Proteins power modern medicine, manufacturing and diagnostics. Engineering them is still a slow cycle of mutation, testing and repetition.
We’re developing a platform for Phage-Assisted Continuous Evolution (PACE), connecting a protein’s desired function to a bacteriophage’s ability to reproduce. The better the function, the stronger the selection.
How PACE works
Meet the platform Let biology do the searching.
Keep the process moving.
- 01 Program
Link function to survival.
Engineer phages so their ability to reproduce depends on the protein function we want to evolve.
- 02 Diversify
Make variation continuous.
Introduce genetic variation while phages circulate through miniature reaction vessels.
- 03 Select
Let better variants thrive.
Functional variants replicate. Continuous flow carries out the selection, generation after generation.
- 04 Repeat
Observe. Keep evolving.
Fluorescence provides a readout of activity while our control system keeps the experiment running.
Our platformDesigned and built in-house
One platform.
Every part, connected.
Continuous evolution needs more than biology. We’re bringing the entire experiment together, from the reaction vessel to the control software.
Built around
Precision fluidics
Keep the
conditions right.
Peristaltic pumps and optical density sensors work together to regulate feeding and monitor bacterial growth.
Automation software
Close the
feedback loop.
Our in-house control stack brings together real-time monitoring, pump control and data logging. It is designed for experiments that run for days.
Current milestoneBuilt. Assembled.
Built. Assembled.
Preparing for proof of concept.
Our first planned evolution run targets T7 RNA polymerase, adapting it to recognise a new genetic target.
Discuss our next milestones- System
- Fully assembled
- Current stage
- Final validation
- Next milestone
- First proof-of-concept run
The teamETH Zürich
Three founders.
A shared drive to build.
What began as a protein expression experiment at the ETH Student Project House grew into an ambition to rethink how proteins are engineered.
Vincent Peuker
EmailCEO & Co-Founder
Biotechnology at ETH Zürich. Leading scientific strategy, molecular biology and the vision for EvoLapse.
Biology & strategy
Jonas Fischer
EmailCTO & Co-Founder
Biochemistry at ETH Zürich. Building the reactors, fluidics, sensors and software that bring the platform to life.
Hardware & automation
Basil Stricker
EmailCOO & Co-Founder
Biochemistry at ETH Zürich. Connecting day-to-day experiments, strain maintenance and protein validation.
Experiments & validation
Built from curiosity.
Developed in Zürich.
We design, build and test at the Student Project House Life Science Lab on ETH Zürich’s Hönggerberg campus. Our platform has been developed from scratch by our team, with approximately a year of self-funded work.
Let’s move biology forwardZürich, Switzerland
The next evolution
starts with a conversation.
Whether you’re exploring an investment, a research collaboration, or simply want to learn more, we’d like to hear from you.